Virus-like particles: models for assembly studies and foreign epitope carriers.
نویسندگان
چکیده
منابع مشابه
T cell-independent type I antibody response against B cell epitopes expressed repetitively on recombinant virus particles.
Recombinant viral or virus-like particles offer new tools for vaccine development. This study investigated hepatitis B core antigen (HBcAg) capsids and RNA phage Qbeta coats as carriers of a foreign epitope to induce antibody responses in mice. HBcAg capsids were shown to induce T cell-independent (TI) antibodies. We found that these particles behave as antigen-specific TI type 1 (TI-1) Ag comp...
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عنوان ژورنال:
- Progress in nucleic acid research and molecular biology
دوره 80 شماره
صفحات -
تاریخ انتشار 2005